PgFur participates differentially in expression of virulence factors in more virulent A7436 and less virulent ATCC 33277 Porphyromonas gingivalis strains
نویسندگان
چکیده
منابع مشابه
Comparative gene expression analysis of Porphyromonas gingivalis ATCC 33277 in planktonic and biofilms states
BACKGROUND AND OBJECTIVE Porphyromonas gingivalis is a keystone pathogen in the onset and progression of periodontitis. Its pathogenicity has been related to its presence and survival within the subgingival biofilm. The aim of the present study was to compare the genome-wide transcription activities of P. gingivalis in biofilm and in planktonic growth, using microarray technology. MATERIAL AN...
متن کاملGenome Sequence of Porphyromonas gingivalis Strain A7436.
Porphyromonas gingivalis is strongly associated with periodontitis. P. gingivalis strain trafficking and tissue homing differ widely, even among presumptive closely related strains, such as W83 and A7436. Here, we present the genome sequence of A7436 with a single contig of 2,367,029 bp and a G+C content of 48.33%.
متن کاملComparative whole-genome analysis of virulent and avirulent strains of Porphyromonas gingivalis.
We used Porphyromonas gingivalis gene microarrays to compare the total gene contents of the virulent strain W83 and the avirulent type strain, ATCC 33277. Signal ratios and scatter plots indicated that the chromosomes were very similar, with approximately 93% of the predicted genes in common, while at least 7% of them showed very low or no signals in ATCC 33277. Verification of the array result...
متن کاملHUMORAL IMMUNE RESPONSE TO ANTIGENS OF Porphyromonas gingivalis ATCC 33277 IN CHRONIC PERIODONTITIS
INTRODUCTION Periodontitis is a chronic disease that results from an interaction of a mixed bacterial challenge and the host response. OBJECTIVE The purposes of this study were to evaluate the IgG serum levels to Porphyromonas gingivalis antigens by ELISA in individuals with different periodontal conditions correlated with clinical parameters, and to analyze the immunoreactivity profiles by W...
متن کاملDetermination of the Genome Sequence of Porphyromonas gingivalis Strain ATCC 33277 and Genomic Comparison with Strain W83 Revealed Extensive Genome Rearrangements in P. gingivalis
The gram-negative anaerobic bacterium Porphyromonas gingivalis is a major causative agent of chronic periodontitis. Porphyromonas gingivalis strains have been classified into virulent and less-virulent strains by mouse subcutaneous soft tissue abscess model analysis. Here, we present the whole genome sequence of P. gingivalis ATCC 33277, which is classified as a less-virulent strain. We identif...
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ژورنال
عنوان ژورنال: BMC Microbiology
سال: 2019
ISSN: 1471-2180
DOI: 10.1186/s12866-019-1511-x